Oxygen Consumption of the Kidney
نویسندگان
چکیده
منابع مشابه
Renal transplantation induces mitochondrial uncoupling, increased kidney oxygen consumption, and decreased kidney oxygen tension.
Hypoxia is an acknowledged pathway to renal injury and ischemia-reperfusion (I/R) and is known to reduce renal oxygen tension (Po2). We hypothesized that renal I/R increases oxidative damage and induces mitochondrial uncoupling, resulting in increased oxygen consumption and hence kidney hypoxia. Lewis rats underwent syngenic renal transplantation (TX) and contralateral nephrectomy. Controls wer...
متن کاملKidney oxygen consumption, carbonic anhydrase, and proton secretion.
Oxygen consumed by the kidney (Q(O(2))) is primarily obligated to sodium reabsorption (T(Na)). The relationship of Q(O(2)) to T(Na) (Q(O(2))/T(Na)) may be altered by hormones and autacoids. To examine whether Q(O(2))/T(Na) depends on the mechanism of sodium reabsorption, we first evaluated the effects on Q(O(2)) and Q(O(2))/T(Na) of benzolamide (BNZ), a proximal diuretic that works by inhibitin...
متن کاملRat atrial natriuretic peptides inhibit oxygen consumption by rat kidney.
The inhibitory effect of high and low molecular weight native and synthetic rat atrial peptides on oxygen consumption in isolated rat kidney mitochondria and slices was measured. Oxygen consumption by mitochondria was measured in the presence of succinate and/or adenosine diphosphate, furosemide, and low and high molecular weight native and synthetic rat atrial peptides. After the addition of s...
متن کاملRemnant Kidney Oxygen Consumption: Hypermetabolism or Hyperbole?1
On the basis of observations in surgically created remnant kidneys of rat and dog, a novel hypothesis for progressive injury in the setting of reduced renal mass has been put forth. Both rat and dog remnant kidneys exhibit significant hypertrophy that is accompanied by an increased rate of oxygen consumption (Qo2) per remaining nephron but not per gram of tissue. This putative “hypermetabolism”...
متن کاملI-11: The Use of Oxygen Consumption for Oocyte and Embryo Selection
Assisted human reproduction is characterized by a high variability in results regarding pregnancy and birth rates. In fact, in a cohort of fertilized oocytes from the same stimulation cycle, the development rate varies drastically, even though produced at the same time and under similar conditions. This variability results in large differences in implantation potential of human embryos develope...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Proceedings of the Imperial Academy
سال: 1926
ISSN: 0369-9846,1881-1140
DOI: 10.2183/pjab1912.2.431